Women Infected with HIV Type 1 Brazilian Variant, Subtype B (B'-GWGR Motif) Have Slower Progression to AIDS, Compared with Patients Infected with Subtype B (B-GPGR Motif) | Zendy

A Brito | Zendy; Shirley Vasconcelos Komninakis | Zendy; P. Novoa | Zendy; Ramany Oliveira | Zendy; Luiz Augusto Marcondes Fonseca | Zendy; A.J.S. Duarte | Zendy; Jorge Casseb | Zendy

Open Access

Women Infected with HIV Type 1 Brazilian Variant, Subtype B (B'-GWGR Motif) Have Slower Progression to AIDS, Compared with Patients Infected with Subtype B (B-GPGR Motif)

Author(s) -

A Brito,

Shirley Vasconcelos Komninakis,

P. Novoa,

Ramany Oliveira,

Luiz Augusto Marcondes Fonseca,

A.J.S. Duarte,

Jorge Casseb

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/508875

Subject(s) - motif (music) , medicine , human immunodeficiency virus (hiv) , virology , sida , viral disease , physics , acoustics

The Brazilian variant of human immunodeficiency virus (HIV) type 1 (HIV-1) subtype B (serotype B'-GWGR) has a tryptophan replacing a proline in position 328 of the HIV-1 envelope, a feature that may induce a different HIV disease progression. We aimed to evaluate the role of the B subtypes of HIV-1 (serotypes B-GPGR and B'-GWGR) on HIV disease progression.

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