Randomized, Double‐Blind, Placebo‐Controlled Efficacy Trial of a Bivalent Recombinant Glycoprotein 120 HIV‐1 Vaccine among Injection Drug Users in Bangkok, Thailand
Author(s) -
Punnee Pitisuttithum,
Peter B. Gilbert,
Marc Gurwith,
William L. Heyward,
Michael Martin,
Fritz van Griensven,
Dale J. Hu,
Jordan W. Tappero,
Kachit Choopanya
Publication year - 2006
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/508748
Subject(s) - medicine , placebo , vaccine trial , hiv vaccine , clinical endpoint , immunology , vaccine efficacy , randomized controlled trial , confidence interval , incidence (geometry) , viral load , vaccination , virology , clinical trial , human immunodeficiency virus (hiv) , pathology , alternative medicine , physics , optics
In Thailand, phase 1/2 trials of monovalent subtype B and bivalent subtype B/E (CRF01_AE) recombinant glycoprotein 120 human immunodeficiency virus type 1 (HIV-1) vaccines were successfully conducted from 1995 to 1998, prompting the first HIV-1 vaccine efficacy trial in Asia.
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