Reactivation of 2 Genetically Distinct Varicella-Zoster Viruses in the Same Individual | Zendy

Yusri Taha | Zendy; Fiona Scott | Zendy; S. P. Parker | Zendy; Denise Syndercombe Court | Zendy; Mark L. Quinlivan | Zendy; Judith Breuer | Zendy

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Reactivation of 2 Genetically Distinct Varicella-Zoster Viruses in the Same Individual

Author(s) -

Yusri Taha,

Fiona Scott,

S. P. Parker,

Denise Syndercombe Court,

Mark L. Quinlivan,

Judith Breuer

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/508539

Subject(s) - chickenpox , virology , varicella zoster virus , biology , virus , immunity , genotype , pathogenesis , immunology , genetics , gene , immune system

Varicella-zoster viruses recovered from 2 episodes of herpes zoster in an immunocompetent man were found to be different genotypes. The fact that the 2 isolates came from the same individual was confirmed by DNA fingerprinting. Immunity following chickenpox may not always protect against systemic reinfection. This finding raises questions about varicella-zoster virus pathogenesis and may have an impact on public health policy.

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