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The World Health Organization (WHO) recommends the discontinuation of oral poliovirus vaccine after eradication of wild poliovirus. Studies assessing inactivated poliovirus vaccine (IPV) immunogenicity in tropical countries, using the WHO Expanded Programme on Immunization (EPI) schedule, have been limited.

Serologic Response to Inactivated Poliovirus Vaccine: A Randomized Clinical Trial Comparing 2 Vaccination Schedules in Puerto Rico