HIV-Associated Monoclonal Gammopathy: A Retrospective Analysis of 25 Patients | Zendy

Sameh Amara | Zendy; Bruce J. Dezube | Zendy; Timothy P. Cooley | Zendy; Liron Pantanowitz | Zendy; David M. Aboulafia | Zendy

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HIV-Associated Monoclonal Gammopathy: A Retrospective Analysis of 25 Patients

Author(s) -

Sameh Amara,

Bruce J. Dezube,

Timothy P. Cooley,

Liron Pantanowitz,

David M. Aboulafia

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/508351

Subject(s) - medicine , monoclonal gammopathy of undetermined significance , multiple myeloma , gastroenterology , lymphoma , population , plasmacytoma , monoclonal , immunology , immunopathology , hepatitis b virus , macroglobulinemia , antibody , virus , monoclonal antibody , environmental health

Monoclonal gammopathy of undetermined significance (MGUS) is unusual in the general population aged <60 years. Various reports indicate a much higher incidence of monoclonal gammopathy among human immunodeficiency virus (HIV)-infected patients and a significantly younger age at diagnosis. We sought to describe the laboratory findings and clinical course of MGUS, including association with plasma cell disorders, other malignancies, and infections, in 25 HIV-infected patients with a detectable serum monoclonal protein.

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