Open AccessRegulation ofStaphylococcus aureusα‐Toxin Gene(hla)Expression byagr, sarA,andsaeIn Vitro and in Experimental Infective Endocarditis
Author(s) -
Yan Q. Xiong,
Julie Willard,
Michael R. Yeaman,
Ambrose L. Cheung,
Arnold S. Bayer
Publication year - 2006
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/508210
Subject(s) - staphylococcus aureus , infective endocarditis , microbiology and biotechnology , in vitro , toxin , biology , gene expression , gene , medicine , bacteria , genetics , surgery
The Staphylococcus aureus global regulators--agr, sarA, and sae--coordinately control alpha-toxin gene (hla) expression in vitro. However, their relative in vivo contributions to hla expression, particularly in endovascular infections, have not been defined.
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