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The Staphylococcus aureus global regulators--agr, sarA, and sae--coordinately control alpha-toxin gene (hla) expression in vitro. However, their relative in vivo contributions to hla expression, particularly in endovascular infections, have not been defined.

the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases

Regulation ofStaphylococcus aureusα‐Toxin Gene(hla)Expression byagr, sarA,andsaeIn Vitro and in Experimental Infective Endocarditis