Shiga Toxin Activatable by Intestinal Mucus in Escherichia coli Isolated from Humans: Predictor for a Severe Clinical Outcome | Zendy

Martina Bielaszewska | Zendy; A. Friedrich | Zendy; Thomas Aldick | Zendy; R. Schurk-Bulgrin | Zendy; Helge Karch | Zendy

Open Access

Shiga Toxin Activatable by Intestinal Mucus in Escherichia coli Isolated from Humans: Predictor for a Severe Clinical Outcome

Author(s) -

Martina Bielaszewska,

A. Friedrich,

Thomas Aldick,

R. Schurk-Bulgrin,

Helge Karch

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/508195

Subject(s) - microbiology and biotechnology , medicine , escherichia coli , shiga toxin , mucus , toxin , enterobacteriaceae , gastroenterology , biology , biochemistry , gene , ecology

Some Escherichia coli produce Shiga toxin (Stx) in which cytotoxicity is increased (activated) by intestinal mucus and elastase (Stx2d(activatable)). These strains are highly virulent in mice, but their association with human disease is poorly understood. We investigated the prevalence of Stx2d(activatable) among Stx-producing E. coli (STEC) isolated from humans and the association between production of this Stx and the clinical outcome of infection.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research