Cryptococcus gattiiInfection: Characteristics and Epidemiology of Cases Identified in a South African Province with High HIV Seroprevalence, 2002–2004 | Zendy

Juliette Morgan | Zendy; Kerrigan McCarthy | Zendy; Susan Martin Gould | Zendy; Ke Fan | Zendy; Beth A. ArthingtonSkaggs | Zendy; Naureen Iqbal | Zendy; Karen Stamey | Zendy; Rana Hajjeh | Zendy; Mary E. Brandt | Zendy

Open Access

Cryptococcus gattiiInfection: Characteristics and Epidemiology of Cases Identified in a South African Province with High HIV Seroprevalence, 2002–2004

Author(s) -

Juliette Morgan,

Kerrigan McCarthy,

Susan Martin Gould,

Ke Fan,

Beth A. ArthingtonSkaggs,

Naureen Iqbal,

Karen Stamey,

Rana Hajjeh,

Mary E. Brandt

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/507897

Subject(s) - cryptococcus gattii , cryptococcosis , medicine , seroprevalence , epidemiology , cryptococcus , meningitis , coinfection , concomitant , population , cryptococcal meningitis , immunology , human immunodeficiency virus (hiv) , virology , serology , viral disease , pediatrics , microbiology and biotechnology , biology , environmental health , antibody

We describe 46 Cryptococcus gattii-infected persons identified by population-based surveillance conducted in South Africa. Most patients with C. gattii infection presented with meningitis. The mortality rate during hospitalization was 36%. We found no significant differences between persons with and persons without C. gattii infection with regard to clinical presentation, acquired immunodeficiency syndrome diagnosis, concomitant conditions, or prior opportunistic infections. C. gattii isolates had low MICs to the tested antifungal drugs.

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