Genes for the Majority Of Group A Streptococcal Virulence Factors and Extracellular Surface Proteins Do Not Confer an Increased Propensity to Cause Invasive Disease | Zendy

David J. McMillan | Zendy; Robert G. Beiko | Zendy; Robert Geffers | Zendy; Jan Buer | Zendy; Leo M. Schouls | Zendy; Bart J. M. Vlaminckx | Zendy; W J B Wannet | Zendy; Kadaba S. Sriprakash | Zendy; G. S. Chhatwal | Zendy

Open Access

Genes for the Majority Of Group A Streptococcal Virulence Factors and Extracellular Surface Proteins Do Not Confer an Increased Propensity to Cause Invasive Disease

Author(s) -

David J. McMillan,

Robert G. Beiko,

Robert Geffers,

Jan Buer,

Leo M. Schouls,

Bart J. M. Vlaminckx,

W J B Wannet,

Kadaba S. Sriprakash,

G. S. Chhatwal

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/507537

Subject(s) - virulence , disease , gene , biology , genetics , medicine , computational biology , pathology

The factors behind the reemergence of severe, invasive group A streptococcal (GAS) diseases are unclear, but it could be caused by altered genetic endowment in these organisms. However, data from previous studies assessing the association between single genetic factors and invasive disease are often conflicting, suggesting that other, as-yet unidentified factors are necessary for the development of this class of disease.

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