Longitudinal Analysis of Simian Immunodeficiency Virus (SIV) Replication in the Lungs: Compartmentalized Regulation of SIV
Author(s) -
Sheila A. Barber,
Lúcio Gama,
Ming Li,
Tauni Voelker,
John E. Anderson,
M. Christine Zink,
Patrick M. Tarwater,
Lucy M. Carruth,
Janice E. Clements
Publication year - 2006
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/507429
Subject(s) - simian immunodeficiency virus , virology , virus , macaque , viral replication , biology , simian , lentivirus , replication (statistics) , bronchoalveolar lavage , rhesus macaque , human immunodeficiency virus (hiv) , immunology , viral disease , lung , medicine , paleontology
Before the onset of AIDS, replication of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) in the lungs is considered to be latent. When and how virus replication is controlled in the lungs is unclear. In the present study, we examine virus replication in the lungs and in cells recovered from bronchoalveolar lavage (BAL) samples in a comprehensive, longitudinal analysis of an SIV/macaque model.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom