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Low Rates of Streptococcal Pharyngitis and High Rates of Pyoderma in Australian Aboriginal Communities Where Acute Rheumatic Fever Is Hyperendemic
Author(s) -
Malcolm McDonald,
Rebecca J. Towers,
Ross Andrews,
Norma Benger,
Bart J. Currie,
Jonathan R. Carapetis
Publication year - 2006
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/506938
Subject(s) - rheumatic fever , pharyngitis , medicine , pyoderma , group a , pathogenesis , acute rheumatic fever , epidemiology , immunology , streptococcus , dermatology , biology , bacteria , genetics
Acute rheumatic fever is a major cause of heart disease in Aboriginal Australians. The epidemiology differs from that observed in regions with temperate climates; streptococcal pharyngitis is reportedly rare, and pyoderma is highly prevalent. A link between pyoderma and acute rheumatic fever has been proposed but is yet to be proven. Group C beta-hemolytic streptococci and group G beta-hemolytic streptococci have also been also implicated in the pathogenesis.

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