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Use of Vancomycin-Containing Lock or Flush Solutions for Prevention of Bloodstream Infection Associated with Central Venous Access Devices: A Meta-Analysis of Prospective, Randomized Trials
Author(s) -
Nasia Safdar,
D. G. Maki
Publication year - 2006
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/505976
Subject(s) - medicine , vancomycin , randomized controlled trial , heparin , bloodstream infection , meta analysis , confidence interval , central venous catheter , intensive care medicine , population , relative risk , prospective cohort study , surgery , intensive care , catheter , environmental health , biology , bacteria , genetics , staphylococcus aureus
Prolonged exposure to central venous access devices carries significant risk of device-associated bloodstream infection (BSI), which is associated with morbidity, added health care costs, and attributable mortality. We aimed to determine the efficacy of vancomycin-heparin lock or flush solution in preventing BSI in patients being treated with long-term central venous intravascular devices (IVDs).

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