Topical Iontophoretic Administration of Acyclovir for the Episodic Treatment of Herpes Labialis: A Randomized, Double-Blind, Placebo-Controlled, Clinic-Initiated Trial | Zendy

E. M. Morrel | Zendy; Spotswood L. Spruance | Zendy; Dennis Goldberg | Zendy

Open Access

Topical Iontophoretic Administration of Acyclovir for the Episodic Treatment of Herpes Labialis: A Randomized, Double-Blind, Placebo-Controlled, Clinic-Initiated Trial

Author(s) -

E. M. Morrel,

Spotswood L. Spruance,

Dennis Goldberg

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/505872

Subject(s) - medicine , herpes labialis , double blind , placebo , iontophoresis , aciclovir , dermatology , anesthesia , randomized controlled trial , double blind study , viral disease , surgery , virology , herpesviridae , herpes simplex virus , alternative medicine , virus , pathology , radiology

Multiple studies of the use of acyclovir for the treatment of herpes labialis have suggested that the nominal efficacy of the topical formulation is the result of inadequate penetration of the drug into the target site of infection, the basal epidermis.

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