Time to Initiation of Fluconazole Therapy Impacts Mortality in Patients with Candidemia: A Multi‐Institutional Study | Zendy

Kevin W. Garey | Zendy; M Rege | Zendy; Manjunath P. Pai | Zendy; Dana E. Mingo | Zendy; Katie J. Suda | Zendy; Robin S. Turpin | Zendy; David T. Bearden | Zendy

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Time to Initiation of Fluconazole Therapy Impacts Mortality in Patients with Candidemia: A Multi‐Institutional Study

Author(s) -

Kevin W. Garey,

M Rege,

Manjunath P. Pai,

Dana E. Mingo,

Katie J. Suda,

Robin S. Turpin,

David T. Bearden

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/504810

Subject(s) - fluconazole , medicine , fungemia , candida glabrata , candida tropicalis , candida parapsilosis , candida albicans , retrospective cohort study , mycosis , mortality rate , corpus albicans , surgery , antifungal , microbiology and biotechnology , biology , dermatology

Inadequate antimicrobial treatment is an independent determinant of hospital mortality, and fungal bloodstream infections are among the types of infection with the highest rates of inappropriate initial treatment. Because of significant potential for reducing high mortality rates, we sought to assess the impact of delayed treatment across multiple study sites. The goals our analyses were to establish the frequency and duration of delayed antifungal treatment and to evaluate the relationship between treatment delay and mortality.

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