Linezolid and Serotonergic Drug Interactions: A Retrospective Survey | Zendy

Jeremy Taylor | Zendy; John Wilson | Zendy; Lynn L. Estes | Zendy

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Linezolid and Serotonergic Drug Interactions: A Retrospective Survey

Author(s) -

Jeremy Taylor,

John Wilson,

Lynn L. Estes

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/504809

Subject(s) - medicine , linezolid , serotonergic , drug , retrospective cohort study , pharmacology , intensive care medicine , serotonin , vancomycin , receptor , biology , bacteria , genetics , staphylococcus aureus

Linezolid is a reversible, nonselective monoamine oxidase inhibitor. There are currently 11 published case reports of serotonin syndrome being associated with linezolid and selective serotonin reuptake inhibitors (SSRIs). Controversy exists regarding whether linezolid and SSRIs can be given concomitantly. The purpose of this study was to report the incidence of serotonin syndrome in patients receiving linezolid and SSRIs.

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