Rhabdomyolysis during Therapy with Daptomycin | Zendy

Stephen M. Papadopoulos | Zendy; Amanda M. Ball | Zendy; Susanne Liewer | Zendy; Catherine Martin | Zendy; P. Shane Winstead | Zendy; Benjamin S. Murphy | Zendy

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Rhabdomyolysis during Therapy with Daptomycin

Author(s) -

Stephen M. Papadopoulos,

Amanda M. Ball,

Susanne Liewer,

Catherine Martin,

P. Shane Winstead,

Benjamin S. Murphy

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/504379

Subject(s) - daptomycin , rhabdomyolysis , medicine , incidence (geometry) , creatine kinase , myopathy , surgery , staphylococcus aureus , vancomycin , physics , biology , bacteria , optics , genetics

The use of daptomycin has been associated with an elevation in creatine phosphokinase level, with a reported incidence of 2.8% in phase III clinical trials. Published case reports have documented the presence of myopathy in patients who received daptomycin; however, there have been no previously reported cases of rhabdomyolysis in animals or humans to date. We describe a case of rhabdomyolysis during therapy with daptomycin.

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