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Differences in Clinical Severity between Genotype A and Genotype B Human Metapneumovirus Infection in Children
Author(s) -
Diego Vicente,
M Montes,
Gustavo Cilla,
E.G. PérezYarza,
E Pérez-Trallero
Publication year - 2006
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/504378
Subject(s) - medicine , genotype , human metapneumovirus , metapneumovirus , pneumonia , neonatal intensive care unit , pediatric intensive care unit , immunology , pediatrics , respiratory system , respiratory tract infections , biology , biochemistry , gene
The clinical spectrum of 69 episodes of metapneumovirus pediatric infection (55 episodes caused by genotype A and 14 episodes caused by genotype B) was analyzed. Diagnosis of pneumonia was more common and the illness severity index (determined on the basis of need for hospitalization, oxygen saturation <90%, and intensive care unit stay) was higher for patients with metapneumovirus genotype A infection.

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