Incidence of Guillain‐Barré Syndrome among Patients withCampylobacterInfection: A General Practice Research Database Study
Author(s) -
Clarence C. Tam,
Laura C. Rodrigues,
Irene Petersen,
Amir Islam,
Andrew Hayward,
S. O’Brien
Publication year - 2006
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/504294
Subject(s) - campylobacter , incidence (geometry) , medicine , guillain barre syndrome , enteritis , population , cohort , cohort study , pediatrics , intensive care medicine , biology , environmental health , bacteria , physics , genetics , optics
The association between Campylobacter infection and subsequent Guillain-Barré syndrome (GBS) has been well documented. To date, however, there exists no direct estimate of the incidence of GBS among patients with Campylobacter infection. Using the General Practice Research Database, we estimate the incidence of GBS in a cohort of patients presenting with Campylobacter enteritis to be 1.17/1000 person-years, a rate 77 times greater than that in the general population. The probability that an individual who develops Campylobacter enteritis will also develop GBS during the subsequent 2-month period is <2/10,000.
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