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A Comparison between Abacavir and Efavirenz as the Third Drug Used in Combination with a Background Therapy Regimen of 2 Nucleoside Reverse‐Transcriptase Inhibitors in Patients with Initially Suppressed Viral Loads
Author(s) -
Alessandro CozziLepri,
Andrea De Luca,
Andrew Phillips,
Marco Bongiovanni,
Simona Di Giambenedetto,
Maurizio Mena,
Maria Cristina Moioli,
M. Arlotti,
Laura Sighinolfi,
Pasquale Narciso,
Miriam Lichtner,
Roberto Cauda,
Antonella d’Arminio Monforte
Publication year - 2006
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/504265
Subject(s) - abacavir , efavirenz , stavudine , lamivudine , didanosine , medicine , zidovudine , reverse transcriptase inhibitor , regimen , viral load , virology , pharmacology , gastroenterology , antiretroviral therapy , human immunodeficiency virus (hiv) , viral disease , virus , hepatitis b virus
Our objective was to compare the rate of viral rebound and therapy failure in patients receiving abacavir or efavirenz as the third drug (in addition to 2 non-abacavir nucleosides) in combination antiretroviral therapy (cART) and to compare the rate of metabolic alteration associated with these regimens.

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