Cytokine Modulation of the Innate Immune Response in Feline Immunodeficiency Virus–Infected Cats | Zendy

Gregg A. Dean | Zendy; Alora LaVoy | Zendy; Jennifer H. Yearley | Zendy; Christine Stanton | Zendy

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Cytokine Modulation of the Innate Immune Response in Feline Immunodeficiency Virus–Infected Cats

Author(s) -

Gregg A. Dean,

Alora LaVoy,

Jennifer H. Yearley,

Christine Stanton

Publication year - 2006

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/503873

Subject(s) - feline immunodeficiency virus , innate immune system , immune system , immunology , biology , cats , virology , interferon gamma , virus , lentivirus , medicine , viral disease

In vitro data suggest that innate immune function in human immunodeficiency virus type 1-infected patients is compromised; however, in vivo studies are lacking. Feline immunodeficiency virus (FIV) infection in cats provides an excellent model to explore innate immune function in vivo. The innate response against Listeria monocytogenes is well understood, making it a useful immune probe.

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