Nasopharyngeal Shedding of Severe Acute Respiratory Syndrome--Associated Coronavirus Is Associated with Genetic Polymorphisms
Author(s) -
W.-J. Chen,
Jun-Young Yang,
JihHui Lin,
Cathy S.J. Fann,
V. Osyetrov,
ChwanChuen King,
Y.-M. A. Chen,
Hsiao-Liang Chang,
Hung-Wei Kuo,
Fan Liao,
M S Ho
Publication year - 2006
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/503843
Subject(s) - medicine , single nucleotide polymorphism , immunology , coronavirus , viral load , viral shedding , virus , virology , genotype , biology , gene , genetics , covid-19 , disease , infectious disease (medical specialty)
A high initial or peak severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) load in nasopharyngeal specimens was shown to be associated with a high mortality rate. Because all infected individuals were devoid of preeexisting protective immunity against SARS-CoV, the biological basis for the variable virus burdens in different patients remains elusive.
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