Indirect Effect of Conjugate Vaccine on Adult Carriage ofStreptococcus pneumoniae:An Explanation of Trends in Invasive Pneumococcal Disease | Zendy

Laura L. Hammitt | Zendy; Dana L. Bruden | Zendy; Jay C. Butler | Zendy; Henry C. Baggett | Zendy; Debby Hurlburt | Zendy; Alisa Reasonover | Zendy; Thomas W. Hennessy | Zendy

Open Access

Indirect Effect of Conjugate Vaccine on Adult Carriage ofStreptococcus pneumoniae:An Explanation of Trends in Invasive Pneumococcal Disease

Author(s) -

Laura L. Hammitt,

Dana L. Bruden,

Jay C. Butler,

Henry C. Baggett,

Debby Hurlburt,

Alisa Reasonover,

Thomas W. Hennessy

Publication year - 2006

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/503805

Subject(s) - carriage , streptococcus pneumoniae , serotype , pneumococcal conjugate vaccine , pneumococcal infections , medicine , vaccination , penicillin , antibiotic resistance , pneumococcal vaccine , microbiology and biotechnology , immunology , virology , antibiotics , biology , pathology

Use of heptavalent protein-polysaccharide pneumococcal conjugate vaccine (PCV7) has been associated with decreases in PCV7-type invasive pneumococcal disease and nasopharyngeal (NP) carriage in children. Vaccine use has also indirectly decreased the rate of invasive disease in adults, presumably through decreased transmission of pneumococci from vaccinated children to adults.

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