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Deep-Seated Resistance in Relapsed Paratyphoid Fever
Author(s) -
Graham Cooke,
Fiona J. Cooke,
M. Stone,
A. Keith Turner,
Adil AlNahhas,
Z. Win,
John Wain,
Thomas R. Rogers,
Jon S. Friedland,
K. B. Bamford
Publication year - 2006
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/503562
Subject(s) - medicine , aortitis , positron emission tomography , ciprofloxacin , virology , radiology , microbiology and biotechnology , antibiotics , biology , aorta
We describe a case of relapsed paratyphoid fever in which the isolate had reduced susceptibility to ciprofloxacin due to a rare mutation within the gyrA gene. 18fluorodeoxyglucose positron emission tomography scanning identified deep-seated infection including unsuspected aortitis and highlights the utility of novel imaging techniques to improve our understanding and treatment of this disease.

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