Association between rmpA and magA Genes and Clinical Syndromes Caused by Klebsiella pneumoniae in Taiwan
Author(s) -
WenLiang Yu,
WenChien Ko,
Kuo-Chen Cheng,
H.-C. Lee,
DS Ke,
ChienChang Lee,
Chang-Phone Fung,
YiPing Chuang
Publication year - 2006
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/503420
Subject(s) - klebsiella pneumoniae , medicine , gene , microbiology and biotechnology , klebsiella , immunology , genetics , biology , escherichia coli
The association of the magA gene with the hypermucoviscosity phenotype relevant to the pathogenesis of Klebsiella pneumoniae liver abscess has been reported in Taiwan. Similarly, the rmpA gene, known as a positive regulator of extracapsular polysaccharide synthesis that confers a mucoid phenotype, may be another candidate gene causing hypermucoviscosity. However, the association of rmpA with K. pneumoniae clinical syndromes is unreported. We aimed to investigate the clinical correlation between rmpA and primary Klebsiella abscess, focusing on sites other than the liver.
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