Antigenic Shift and Increased Incidence of Meningococcal Disease
Author(s) -
Lee H. Harrison,
Keith A. Jolley,
Kathleen A. Shutt,
Jane W. Marsh,
Mary M. O’Leary,
Laurie Thomson Sanza,
Martin Maiden
Publication year - 2006
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/501371
Subject(s) - meningococcal disease , neisseria meningitidis , typing , incidence (geometry) , antigen , population , biology , virology , serotype , multilocus sequence typing , microbiology and biotechnology , gene , medicine , immunology , genetics , genotype , bacteria , physics , environmental health , optics
The incidence of serogroup C and Y meningococcal disease increased in the United States during the 1990s. The cyclical nature of endemic meningococcal disease remains unexplained. The purpose of this study was to investigate the mechanisms associated with the increase in the incidence of meningococcal disease.
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