Liver‐Stage Development ofPlasmodium falciparum,in a Humanized Mouse Model | Zendy

Serban Morosan | Zendy; Stéphanie HezDeroubaix | Zendy; F. Lunel | Zendy; Laurent Rénia | Zendy; Carlo Giannini | Zendy; Nico van Rooijen | Zendy; Sérena Battaglia | Zendy; Catherine Blanc | Zendy; W. Eling | Zendy; Robert W. Sauerwein | Zendy; L Hannoun | Zendy; Jacques Belghiti | Zendy; Christian Bréchot | Zendy; Dina Kremsdorf | Zendy; Pierre Druilhe | Zendy

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Liver‐Stage Development ofPlasmodium falciparum,in a Humanized Mouse Model

Author(s) -

Serban Morosan,

Stéphanie HezDeroubaix,

F. Lunel,

Laurent Rénia,

Carlo Giannini,

Nico van Rooijen,

Sérena Battaglia,

Catherine Blanc,

W. Eling,

Robert W. Sauerwein,

L Hannoun,

Jacques Belghiti,

Christian Bréchot,

Dina Kremsdorf,

Pierre Druilhe

Publication year - 2006

Publication title -

the journal of infectious diseases

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/500840

Subject(s) - plasmodium falciparum , biology , malaria , immunology , xenotransplantation , in vivo , humanized mouse , hepatocyte , in vitro , genetically modified mouse , immunity , circumsporozoite protein , secretion , hepatitis , virology , transgene , transplantation , immune system , medicine , endocrinology , gene , biochemistry , microbiology and biotechnology

The liver stage of the human malaria parasite Plasmodium falciparum is the least known, yet it holds the greatest promise for the induction of sterile immunity and the development of novel drugs. Progress has been severely limited by the lack of adequate in vitro and in vivo models.

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