CD8+T Cells in HIV Disease Exhibit Cytokine Receptor Perturbation and Poor T Cell Receptor Activation but Are Responsive to γ‐Chain Cytokine–Driven Proliferation | Zendy

Savita Pahwa | Zendy; Thomas W. McCloskey | Zendy; Olga C. Aroniadis | Zendy; Nataša Štrbo | Zendy; Subramaniam Krishnan | Zendy

Open Access

CD8⁺T Cells in HIV Disease Exhibit Cytokine Receptor Perturbation and Poor T Cell Receptor Activation but Are Responsive to γ‐Chain Cytokine–Driven Proliferation

Author(s) -

Savita Pahwa,

Thomas W. McCloskey,

Olga C. Aroniadis,

Nataša Štrbo,

Subramaniam Krishnan

Publication year - 2006

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/500471

Subject(s) - immunology , cd8 , cytokine , interleukin 15 , biology , t cell , cytotoxic t cell , memory t cell , aldesleukin , il 2 receptor , immune system , interleukin 2 , interleukin , in vitro , biochemistry

Cytokines are important for inducing T cell maturation, proliferation, and survival. Despite the known dysregulation of cytokines in human immunodeficiency virus (HIV) infection, cytokine receptor expression is relatively unexplored.

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