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Successful Treatment of Staphylococcal Toxic Shock Syndrome with Linezolid: A Case Report and In Vitro Evaluation of the Production of Toxic Shock Syndrome Toxin Type 1 in the Presence of Antibiotics
Author(s) -
Dennis L. Stevens,
Randi J. Wallace,
S. M. Hamilton,
Amy E. Bryant
Publication year - 2006
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/500265
Subject(s) - linezolid , medicine , antibiotics , toxic shock syndrome , shock (circulatory) , toxin , in vitro , microbiology and biotechnology , staphylococcus aureus , bacteria , vancomycin , biology , biochemistry , genetics
Figure 1. Antibiotic effects on the growth of Staphylococcus aureus and the production of toxic shock syndrome toxin (TSST)–1. The patient’s strain of S. aureus was cultured in the absence or presence of antibiotics at the indicated final concentrations. Antibiotics were added 4 h after initiation of cultures. Bacterial growth (A) and TSST-1 production (B) were measured by plate counts and ELISA assay, respectively. Data are from 1 representative experiment of 3 and represent the mean of duplicate measurements SD. CFU, colony-forming units. www2.infinit.com/cgi-bin/imprimer.cgi?idp1 48834. Accessed 24 January 2006.

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