Ganciclovir Is Associated with Low or Undetectable Epstein-Barr Virus DNA Load in Cerebrospinal Fluid of Patients with HIV-Related Primary Central Nervous System Lymphoma | Zendy

Simona Bossolasco | Zendy; Kerstin I. Falk | Zendy; Maurilio Ponzoni | Zendy; N. Ceserani | Zendy; Fulvio Crippa | Zendy; Adriano Lazzarin | Zendy; Annika Linde | Zendy; Paola Cinque | Zendy

Open Access

Ganciclovir Is Associated with Low or Undetectable Epstein-Barr Virus DNA Load in Cerebrospinal Fluid of Patients with HIV-Related Primary Central Nervous System Lymphoma

Author(s) -

Simona Bossolasco,

Kerstin I. Falk,

Maurilio Ponzoni,

N. Ceserani,

Fulvio Crippa,

Adriano Lazzarin,

Annika Linde,

Paola Cinque

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/499956

Subject(s) - ganciclovir , primary central nervous system lymphoma , cerebrospinal fluid , medicine , lymphoma , viral load , epstein–barr virus , virus , herpesviridae , cytomegalovirus , virology , gastroenterology , chemotherapy , human cytomegalovirus , immunology , viral disease

Epstein-Barr virus (EBV) is pathogenically linked to human immunodeficiency virus (HIV)-related primary central nervous system lymphoma (PCNSL) and is found in virtually all HIV-related PCNSL cases. The objective of this study was to assess the effect of ganciclovir on EBV DNA replication in patients with HIV-related PCNSL.

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