Different Rates of Disease Progression of HIV Type 1 Infection in Tanzania Based on Infecting Subtype
Author(s) -
Ashwin Vasan,
Boris Renjifo,
Ellen Hertzmark,
Beth Chaplin,
Gernard Msamanga,
Max Essex,
Wafaie Fawzi,
David J. Hunter
Publication year - 2006
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/499952
Subject(s) - medicine , viral load , hazard ratio , immunology , confidence interval , proportional hazards model , tanzania , disease , viral disease , sida , relative risk , cohort study , virology , virus , environmental science , environmental planning
Many different subtypes of human immunodeficiency virus (HIV) type 1 have been identified, particularly in sub-Saharan Africa. However, much remains unknown regarding the relative pathogenicity of these subtypes and their influence on the clinical progression of HIV infection. We examined prospectively the associations between HIV-1 subtypes A, C, and D and recombinant viruses, as well as the rates of disease progression in a cohort of seropositive women from Dar es Salaam, Tanzania.
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