Vigorous Hepatitis C Virus–Specific CD4+and CD8+T Cell Responses Induced by Protein Immunization in the Presence of Montanide ISA720 plus Synthetic Oligodeoxynucleotides Containing Immunostimulatory Cytosine‐Guanine Dinucleotide Motifs | Zendy

Fuminaka Sugauchi | Zendy; Richard Y.H. Wang | Zendy; Qi Qiu | Zendy; Bo Jin | Zendy; Harvey J. Alter | Zendy; J. WaiKuo Shih | Zendy

Open Access

Vigorous Hepatitis C Virus–Specific CD4⁺and CD8⁺T Cell Responses Induced by Protein Immunization in the Presence of Montanide ISA720 plus Synthetic Oligodeoxynucleotides Containing Immunostimulatory Cytosine‐Guanine Dinucleotide Motifs

Author(s) -

Fuminaka Sugauchi,

Richard Y.H. Wang,

Qi Qiu,

Bo Jin,

Harvey J. Alter,

J. WaiKuo Shih

Publication year - 2006

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/499823

Subject(s) - cpg oligodeoxynucleotide , biology , virology , microbiology and biotechnology , t cell , cpg site , cd8 , dna vaccination , antibody , cytotoxic t cell , immune system , immunology , immunization , dna methylation , biochemistry , gene expression , gene , in vitro

A prophylactic vaccine for hepatitis C virus (HCV) requires generation of strong humoral as well as CD4(+) and CD8(+) T cell responses.

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