Temporal Changes in Streptococcal M Protein Types and the Near-Disappearance of Acute Rheumatic Fever in the United States | Zendy

Stanford T. Shulman | Zendy; Gene H. Stollerman | Zendy; Bernard Beall | Zendy; James B. Dale | Zendy; Robert R. Tanz | Zendy

Open Access

Temporal Changes in Streptococcal M Protein Types and the Near-Disappearance of Acute Rheumatic Fever in the United States

Author(s) -

Stanford T. Shulman,

Gene H. Stollerman,

Bernard Beall,

James B. Dale,

Robert R. Tanz

Publication year - 2006

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/499812

Subject(s) - medicine , acute rheumatic fever , rheumatic fever , incidence (geometry) , streptococcal infections , immunology , pediatrics , physics , optics

The explanation for the very substantial decrease in the incidence of acute rheumatic fever in the United States, particularly over the past 50 years, is unclear. It has been proposed that certain M types of group A streptococci (GAS) include strains that are particularly rheumatogenic and that others are nonrheumatogenic.

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