Antiangiogenic Effect of Erythromycin: An In Vitro Model ofBartonella quintanaInfection | Zendy

Soraya Meghari | Zendy; JeanMarc Rolain | Zendy; Georges E. Grau | Zendy; Esther Platt | Zendy; Lina Barrassi | Zendy; JeanLouis Mège | Zendy; Didier Raoult | Zendy

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Antiangiogenic Effect of Erythromycin: An In Vitro Model ofBartonella quintanaInfection

Author(s) -

Soraya Meghari,

JeanMarc Rolain,

Georges E. Grau,

Esther Platt,

Lina Barrassi,

JeanLouis Mège,

Didier Raoult

Publication year - 2006

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/499276

Subject(s) - erythromycin , bacillary angiomatosis , biology , microbiology and biotechnology , doxycycline , mutant , endothelial stem cell , antibiotics , in vitro , immunology , biochemistry , gene , bartonella henselae , serology , antibody

Bartonella quintana, the etiological agent of bacillary angiomatosis (BA), causes endothelial cell proliferation. Erythromycin has dramatic effects on BA, and the effects are largely unexplained by the compound's bacteriostatic properties. Our aim here was to evaluate the possibility that erythromycin alters angiogenesis.

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