The Duration of Hypotension before the Initiation of Antibiotic Treatment Is a Critical Determinant of Survival in a Murine Model ofEscherichia coliSeptic Shock: Association with Serum Lactate and Inflammatory Cytokine Levels | Zendy

Anand Kumar | Zendy; Cameron Haery | Zendy; Bhanu Paladugu | Zendy; Aseem Kumar | Zendy; Simon Symeoneides | Zendy; Leo Taiberg | Zendy; Jailan Osman | Zendy; Gordon M. Trenholme | Zendy; Steven M. Opal | Zendy; Roy D. Goldfarb | Zendy; Joseph E. Parrillo | Zendy

Open Access

The Duration of Hypotension before the Initiation of Antibiotic Treatment Is a Critical Determinant of Survival in a Murine Model ofEscherichia coliSeptic Shock: Association with Serum Lactate and Inflammatory Cytokine Levels

Author(s) -

Anand Kumar,

Cameron Haery,

Bhanu Paladugu,

Aseem Kumar,

Simon Symeoneides,

Leo Taiberg,

Jailan Osman,

Gordon M. Trenholme,

Steven M. Opal,

Roy D. Goldfarb,

Joseph E. Parrillo

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/498909

Subject(s) - septic shock , antibiotics , medicine , shock (circulatory) , hemodynamics , sepsis , tumor necrosis factor alpha , anesthesia , biology , microbiology and biotechnology

This study was designed to examine the relationship between the timing of antibiotic treatment and both survival rates and hemodynamic/inflammatory correlates of survival in a murine model of Escherichia coli septic shock.

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