Impact of Trimethoprim‐Sulfamethoxazole Prophylaxis on Falciparum Malaria Infection and Disease | Zendy

Mahamadou A. Théra | Zendy; Paul S. Sehdev | Zendy; Drissa Coulibaly | Zendy; Karim Traoré | Zendy; Mamane Nassirou Garba | Zendy; Yacouba Cissoko | Zendy; Abdoulaye K. Koné | Zendy; Ando B. Guindo | Zendy; Alassane Dicko | Zendy; Abdoul Habib Béavogui | Zendy; Abdoulaye Djimdé | Zendy; Kirsten E. Lyke | Zendy; Dapa A. Diallo | Zendy; Ogobara K. Doumbo | Zendy; Christopher V. Plowe | Zendy

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Impact of Trimethoprim‐Sulfamethoxazole Prophylaxis on Falciparum Malaria Infection and Disease

Author(s) -

Mahamadou A. Théra,

Paul S. Sehdev,

Drissa Coulibaly,

Karim Traoré,

Mamane Nassirou Garba,

Yacouba Cissoko,

Abdoulaye K. Koné,

Ando B. Guindo,

Alassane Dicko,

Abdoul Habib Béavogui,

Abdoulaye Djimdé,

Kirsten E. Lyke,

Dapa A. Diallo,

Ogobara K. Doumbo,

Christopher V. Plowe

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/498249

Subject(s) - sulfamethoxazole , sulfadoxine , malaria , trimethoprim , medicine , pyrimethamine , malaria prophylaxis , plasmodium falciparum , drug resistance , human immunodeficiency virus (hiv) , immunology , virology , antibiotics , microbiology and biotechnology , biology

Trimethoprim-sulfamethoxazole (TS) prophylaxis is recommended for persons living with human immunodeficiency virus infection and acquired immunodeficiency syndrome in Africa. TS and the antimalarial combination sulfadoxine-pyrimethamine (SP) share mechanisms of action and resistance patterns, and concerns about the impact of TS resistance on SP efficacy have contributed to reluctance to implement TS prophylaxis in Africa.

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