Effective Combination Therapy Using Interferon- and Interleukin-2 for Disseminated Mycobacterium avium Complex Infection in a Pediatric Patient with AIDS | Zendy

Yukari Sekiguchi | Zendy; Kozo Yasui | Zendy; Toshio Yamazaki | Zendy; Kazunaga Agematsu | Zendy; Norihiro Kobayashi | Zendy; K Koike | Zendy

Open Access

Effective Combination Therapy Using Interferon- and Interleukin-2 for Disseminated Mycobacterium avium Complex Infection in a Pediatric Patient with AIDS

Author(s) -

Yukari Sekiguchi,

Kozo Yasui,

Toshio Yamazaki,

Kazunaga Agematsu,

Norihiro Kobayashi,

K Koike

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/498026

Subject(s) - saccharomyces boulardii , medicine , fluconazole , fungemia , amphotericin b , probiotic , trichosporon , immunology , mycosis , yeast , antifungal , biology , dermatology , genetics , bacteria

A 5-year-old girl presented with disseminated Mycobacterium avium complex infection during advanced human immunodeficiency virus infection. Interferon-gamma or interleukin-2 monotherapy showed only limited effects. Use of a combination of interferon-gamma and interferon-2 resulted in a remarkable improvement in the patient's condition, accompanied by an increase in circulating CD4+ T cells.

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