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A 5-year-old girl presented with disseminated Mycobacterium avium complex infection during advanced human immunodeficiency virus infection. Interferon-gamma or interleukin-2 monotherapy showed only limited effects. Use of a combination of interferon-gamma and interferon-2 resulted in a remarkable improvement in the patient's condition, accompanied by an increase in circulating CD4+ T cells.

clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)

Effective Combination Therapy Using Interferon- and Interleukin-2 for Disseminated Mycobacterium avium Complex Infection in a Pediatric Patient with AIDS