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Application of Hepatitis B Virus Genotyping and Phylogenetic Analysis in Intrafamilial Transmission of Hepatitis B Virus
Author(s) -
ChengLi Lin,
JiaHorng Kao,
BingFang Chen,
PeiJer Chen,
Ming–Yang Lai,
DingShinn Chen
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/497837
Subject(s) - genotyping , hbsag , hepatitis b virus , transmission (telecommunications) , virology , genotype , horizontal transmission , serology , medicine , biology , virus , immunology , genetics , antibody , gene , electrical engineering , engineering
Infection with hepatitis B virus (HBV) in early life frequently results in persistent infection, and clustering of the chronic infection within a family is common. However, the relative contribution of perinatal mother-to-infant transmission or early horizontal transmission to the intrafamilial clustering of HBV infection remains unclear. Therefore, we used HBV genotyping and phylogenetic analysis to elucidate the modes of intrafamilial HBV transmission in Taiwan.

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