Prediction of Neuropsychiatric Adverse Events Associated with Long-Term Efavirenz Therapy, Using Plasma Drug Level Monitoring | Zendy

Félix Gutiérrez | Zendy; Andrés NavarroRuiz | Zendy; Sergio Padilla | Zendy; Raúl LópezAntón | Zendy; Mar Masiá | Zendy; J. Borrás | Zendy; A. Martín-Hidalgo | Zendy

Open Access

Prediction of Neuropsychiatric Adverse Events Associated with Long-Term Efavirenz Therapy, Using Plasma Drug Level Monitoring

Author(s) -

Félix Gutiérrez,

Andrés NavarroRuiz,

Sergio Padilla,

Raúl LópezAntón,

Mar Masiá,

J. Borrás,

A. Martín-Hidalgo

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/497835

Subject(s) - efavirenz , medicine , adverse effect , therapeutic drug monitoring , pharmacotherapy , toxicity , drug , intensive care medicine , antiretroviral therapy , pharmacology , human immunodeficiency virus (hiv) , immunology , viral load

Data on long-term central nervous system (CNS) toxicity associated with efavirenz therapy are scarce, and risk factors remain largely unknown. We aimed to determine whether monitoring the plasma concentration of efavirenz could predict neuropsychiatric adverse events associated with long-term therapy with efavirenz.

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