Association between Human Leukocyte Antigen Class II Alleles and Genotype ofBorrelia burgdorferiin Patients with Early Lyme Disease | Zendy

Gary P. Wormser | Zendy; Richard A. Kaslow | Zendy; Jianming Tang | Zendy; Karen Wade | Zendy; Dionysios Liveris | Zendy; Ira Schwartz | Zendy; Mark S. Klempner | Zendy

Open Access

Association between Human Leukocyte Antigen Class II Alleles and Genotype ofBorrelia burgdorferiin Patients with Early Lyme Disease

Author(s) -

Gary P. Wormser,

Richard A. Kaslow,

Jianming Tang,

Karen Wade,

Dionysios Liveris,

Ira Schwartz,

Mark S. Klempner

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/497693

Subject(s) - lyme disease , borrelia burgdorferi , biology , genotype , erythema migrans , spirochaetaceae , erythema chronicum migrans , immunology , allele , virology , genetics , antibody , lyme borreliosis , gene

On the basis of a polymerase chain reaction-restriction fragment-length polymorphism analysis of the 16S-23S ribosomal DNA intergenic spacer, clinical isolates of Borrelia burgdorferi can be classified into 3 genotypes designated as RST1, RST2, and RST3. RST1 strains are the most pathogenic, and RST3 strains are the least pathogenic.

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