The Role of Epitope Specificity in the Human Opsonic Antibody Response to the Staphylococcal Surface Polysaccharide Poly N‐Acetyl Glucosamine | Zendy

Casie KellyQuintos | Zendy; Andrea Kropec | Zendy; Stacy Briggs | Zendy; Claudia L. Ordoñez | Zendy; Donald A. Goldmann | Zendy; Gerald B. Pier | Zendy

Open Access

The Role of Epitope Specificity in the Human Opsonic Antibody Response to the Staphylococcal Surface Polysaccharide Poly N‐Acetyl Glucosamine

Author(s) -

Casie KellyQuintos,

Andrea Kropec,

Stacy Briggs,

Claudia L. Ordoñez,

Donald A. Goldmann,

Gerald B. Pier

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/497604

Subject(s) - epitope , opsonin , microbiology and biotechnology , staphylococcus aureus , antibody , glucosamine , polysaccharide , micrococcaceae , cystic fibrosis , immunology , antibody response , staphylococcus , chemistry , biology , bacteria , antibacterial agent , antibiotics , biochemistry , genetics

The staphylococcal surface polysaccharide poly N-acetyl glucosamine (PNAG) is a target for killing and protective antibody in animals. We investigated the human antibody response and specificity of binding and opsonic antibodies for different epitopes on PNAG in serum samples from patients with cystic fibrosis (CF) colonized and not colonized with Staphylococcus aureus.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research