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Penicillins for Treatment of Pneumococcal Pneumonia: Does In Vitro Resistance Really Matter?
Author(s) -
Lance R. Peterson
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/497594
Subject(s) - streptococcus pneumoniae , medicine , pneumonia , antibiotic resistance , antibiotics , antimicrobial , respiratory tract infections , pneumococcal infections , microbiology and biotechnology , respiratory tract , intensive care medicine , immunology , respiratory system , biology
The rate of in vitro bacterial resistance to antimicrobial agents is escalating among pathogens that cause the most serious respiratory tract infections. Many reports published during the past few years suggest that this has direct clinical implications. In particular, resistance of Streptococcus pneumoniae to beta-lactam antibiotic therapy has assumed a prominent role in the evolution of guidelines for the initial treatment of respiratory tract infection.

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