Randomized, Double-Blind Comparison of Once-Weekly Dalbavancin versus Twice-Daily Linezolid Therapy for the Treatment of Complicated Skin and Skin Structure Infections
Author(s) -
L. E. Jauregui,
S. Babazadeh,
Elyse Seltzer,
L. Goldberg,
Dainis Krieviņš,
Mitchell J. Frederick,
David Krause,
I. Satilovs,
Žilvinas Endzinas,
J. Breaux,
W. O'Riordan
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/497271
Subject(s) - dalbavancin , medicine , linezolid , randomized controlled trial , dermatology , double blind , skin infection , staphylococcus aureus , pathology , vancomycin , biology , bacteria , genetics , placebo , alternative medicine
Dalbavancin, a novel lipoglycopeptide with a pharmacokinetic profile that allows weekly dosing, is active against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). The efficacy of dalbavancin for treatment of skin and skin structure infections (SSSIs) was demonstrated in a phase 2 study.
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