Impact of Rapid Detection of Viral and Atypical Bacterial Pathogens by Real-Time Polymerase Chain Reaction for Patients with Lower Respiratory Tract Infection
Author(s) -
Jan Jelrik Oosterheert,
Anton M. van Loon,
Rob Schuurman,
Andy I. M. Hoepelman,
Eelko Hak,
Steven Thijsen,
G.D. Nossent,
M. M. E. Schneider,
Willem M. N. Hustinx,
Marc J. M. Bonten
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/497134
Subject(s) - medicine , streptococcus pneumoniae , confidence interval , respiratory tract infections , antibiotics , lower respiratory tract infection , randomized controlled trial , staphylococcus aureus , gastroenterology , respiratory system , microbiology and biotechnology , bacteria , genetics , biology
Rapid diagnostic tests with a high sensitivity for lower respiratory tract infection (LRTI) could lead to improved patient care and reduce unnecessary antibiotic use and associated costs. Diagnostic yields, feasibility, and costs of real-time polymerase chain reaction (PCR) of nasopharyngeal and oropharyngeal swab specimens in the routine diagnostic work-up for LRTI were determined.
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