In Vitro Activity of Fluoroquinolones against Mycoplasma genitalium and Their Bacteriological Efficacy for Treatment of M. genitalium-Positive Nongonococcal Urethritis in Men | Zendy

Mitsuru Yasuda | Zendy; Satoshi Maeda | Zendy; Takashi Deguchi | Zendy

Open Access

In Vitro Activity of Fluoroquinolones against Mycoplasma genitalium and Their Bacteriological Efficacy for Treatment of M. genitalium-Positive Nongonococcal Urethritis in Men

Author(s) -

Mitsuru Yasuda,

Satoshi Maeda,

Takashi Deguchi

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/496983

Subject(s) - mycoplasma genitalium , gatifloxacin , urethritis , medicine , levofloxacin , sparfloxacin , mycoplasma , microbiology and biotechnology , pelvic inflammatory disease , antibiotics , chlamydia trachomatis , virology , ofloxacin , gynecology , biology , ciprofloxacin

We investigated the minimum inhibitory concentrations of some fluoroquinolones for Mycoplasma genitalium and their bacteriological efficacy in the treatment of M. genitalium-positive nongonococcal urethritis. In vitro, levofloxacin was less active than gatifloxacin, tosufloxacin, and sparfloxacin. In vivo, the bacteriological efficacy of gatifloxacin was superior to that of levofloxacin or tosufloxacin.

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