Serological and Molecular Evidence That Human Herpesvirus 8 Is Endemic among Amerindians in French Guiana | Zendy

Mirdad Kazanji | Zendy; Philippe Dussart | Zendy; Renan Duprez | Zendy; Patricia Tortevoye | Zendy; JeanFrançois Pouliquen | Zendy; Julie Vandekerkhove | Zendy; Pierre Couppié | Zendy; Jacques Morvan | Zendy; Antoine Talarmin | Zendy; Antoine Gessain | Zendy

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Serological and Molecular Evidence That Human Herpesvirus 8 Is Endemic among Amerindians in French Guiana

Author(s) -

Mirdad Kazanji,

Philippe Dussart,

Renan Duprez,

Patricia Tortevoye,

JeanFrançois Pouliquen,

Julie Vandekerkhove,

Pierre Couppié,

Jacques Morvan,

Antoine Talarmin,

Antoine Gessain

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/491744

Subject(s) - serology , seroprevalence , virology , biology , virus , genotype , antibody , gene , immunology , genetics

We evaluated the presence of human herpesvirus 8 (HHV-8) infection among groups of Amerindians in French Guiana. The overall prevalence of antibodies against lytic HHV-8 antigens was 23.0% (180/781), increasing from 18.4% in children <6 years old to approximately 30% in older persons (>45 years). Seroprevalence was higher in Amerindians living in remote localities than it was in those living in the coastal region. Analysis of a 725-base pair fragment of the K1 gene amplified from DNA from a Wayampi Amerindian showed that the virus belonged to molecular subtype E, which has hitherto been found in only a few Amerindians in Brazil and Ecuador.

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