Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV‐1 RNA in Coinfected Zambian Adults | Zendy

Kayvon Modjarrad | Zendy; Isaac Zulu | Zendy; David T. Redden | Zendy; Lungowe Njobvu | Zendy; H. Clifford Lane | Zendy; Zvi Bentwich | Zendy; Sten H. Vermund | Zendy

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Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV‐1 RNA in Coinfected Zambian Adults

Author(s) -

Kayvon Modjarrad,

Isaac Zulu,

David T. Redden,

Lungowe Njobvu,

H. Clifford Lane,

Zvi Bentwich,

Sten H. Vermund

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/444543

Subject(s) - helminths , human immunodeficiency virus (hiv) , immune system , immunology , rna , virology , biology , medicine , gene , biochemistry

Infection with intestinal helminths may stimulate dysfunctional immune responses in human immunodeficiency virus (HIV)-infected persons. Studies have yielded conflicting results regarding the impact of antihelminthic treatment on plasma concentrations of HIV-1 RNA.Methods. We conducted a prospective study of 54 HIV-1- and helminth-coinfected and 57 HIV-1-infected, helminth-uninfected asymptomatic adults living in Lusaka, Zambia, to assess the impact of antihelminthic treatment on plasma concentrations of HIV-1 RNA.

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