Galactomannan Does Not Precede Major Signs on a Pulmonary Computerized Tomographic Scan Suggestive of Invasive Aspergillosis in Patients with Hematological Malignancies | Zendy

Maja Weisser | Zendy; Caitlin R. Rausch | Zendy; A. Droll | Zendy; Mathew Simcock | Zendy; Parham Sendi | Zendy; Ingo G. Steffen | Zendy; Carlos Buitrago | Zendy; Stefan Sonnet | Zendy; Aloïs Gratwohl | Zendy; Jakob Passweg | Zendy; Ursula Flückiger | Zendy

Open Access

Galactomannan Does Not Precede Major Signs on a Pulmonary Computerized Tomographic Scan Suggestive of Invasive Aspergillosis in Patients with Hematological Malignancies

Author(s) -

Maja Weisser,

Caitlin R. Rausch,

A. Droll,

Mathew Simcock,

Parham Sendi,

Ingo G. Steffen,

Carlos Buitrago,

Stefan Sonnet,

Aloïs Gratwohl,

Jakob Passweg,

Ursula Flückiger

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/444462

Subject(s) - medicine , galactomannan , aspergillosis , prospective cohort study , chemotherapy , hematopoietic stem cell transplantation , gastroenterology , induction chemotherapy , transplantation , surgery , radiology , immunology

Detection of serum galactomannan (GM) antigen and presence of the halo sign on a pulmonary computerized tomographic (CT) scan have a high specificity but a low sensitivity to diagnose invasive aspergillosis (IA) in patients at risk for this disease. To our knowledge, the relationship between the time at which pulmonary infiltrates are detected by CT and the time at which GM antigens are detected by enzyme immunoassay (EIA) has not been studied.

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