Detection of Severe Acute Respiratory Syndrome Coronavirus in the Brain: Potential Role of the Chemokine Mig in Pathogenesis | Zendy

Jun Xu | Zendy; Shan Zhong | Zendy; Jun Liu | Zendy; Ling Li | Zendy; Yanbing Li | Zendy; Xing Wu | Zendy; Zhenlin Li | Zendy; Ping Deng | Zendy; Jiajun Zhang | Zendy; Nanshan Zhong | Zendy; Yi� Ding | Zendy; Yong Jiang | Zendy

Open Access

Detection of Severe Acute Respiratory Syndrome Coronavirus in the Brain: Potential Role of the Chemokine Mig in Pathogenesis

Author(s) -

Jun Xu,

Shan Zhong,

Jun Liu,

Ling Li,

Yanbing Li,

Xing Wu,

Zhenlin Li,

Ping Deng,

Jiajun Zhang,

Nanshan Zhong,

Yi� Ding,

Yong Jiang

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/444461

Subject(s) - chemokine , pathology , coronavirus , biology , reverse transcription polymerase chain reaction , immunology , medicine , virology , inflammation , gene expression , infectious disease (medical specialty) , biochemistry , disease , covid-19 , gene

Previous studies have shown that common human coronavirus might be neurotropic, although it was first isolated as a pathogen of the respiratory tract. We noticed that a few patients with severe acute respiratory syndrome (SARS) experienced central nervous symptoms during the course of illness. In the present study, we isolated a SARS coronavirus strain from a brain tissue specimen obtained from a patient with SARS with significant central nervous symptoms.

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