Immune Reconstitution Syndrome Due to Bacillus Calmette-Guerin after Initiation of Antiretroviral Therapy in Children with HIV Infection | Zendy

Thanyawee Puthanakit | Zendy; Peninnah Oberdorfer | Zendy; Suchart Punjaisee | Zendy; Pornpun Wannarit | Zendy; Thira Sirisanthana | Zendy; Virat Sirisanthana | Zendy

Open Access

Immune Reconstitution Syndrome Due to Bacillus Calmette-Guerin after Initiation of Antiretroviral Therapy in Children with HIV Infection

Author(s) -

Thanyawee Puthanakit,

Peninnah Oberdorfer,

Suchart Punjaisee,

Pornpun Wannarit,

Thira Sirisanthana,

Virat Sirisanthana

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/433177

Subject(s) - medicine , rifampicin , immune system , immunology , incidence (geometry) , isoniazid , immune reconstitution inflammatory syndrome , antiretroviral therapy , confidence interval , tuberculosis , human immunodeficiency virus (hiv) , viral load , pathology , physics , optics

The immune reconstitution syndrome caused by bacillus Calmette-Guerin (BCG) was found in 4 HIV-infected children who were immunized with BCG at birth. The localized, suppurative, BCG-related complications developed within 10 weeks after initiation of antiretroviral therapy. The incidence rate was 2.7 cases per 100 persons (95% confidence interval, 0.7-6.7). Patients responded well to treatment with isoniazid and rifampicin.

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