No Evidence of a Mild Form of Inhalational Bacillus anthracis Infection During a Bioterrorism-Related Inhalational Anthrax Outbreak in Washington, D.C., in 2001
Author(s) -
Henry C. Baggett,
Julia Rhodes,
Scott K. Fridkin,
Conrad P. Quinn,
Jeffrey Hageman,
Cindy R. Friedman,
Clare A. Dykewicz,
Vera Semenova,
Sandra RomeroSteiner,
Cheryl M. Elie,
John A. Jernigan
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/432937
Subject(s) - bacillus anthracis , medicine , outbreak , anthrax vaccines , anthrax toxin , serology , antibody , immunology , virology , immunization , biology , bacteria , dna vaccination , biochemistry , genetics , gene , fusion protein , recombinant dna
The mail-related dispersal of Bacillus anthracis spores in the Washington, D.C., area during October 2001 resulted in 5 confirmed cases of inhalational anthrax. We identified an additional 144 ill persons who were potentially exposed to aerosolized spores and whose symptoms were compatible with early inhalational anthrax but whose clinical course and nonserologic laboratory evaluation revealed no evidence for B. anthracis infection. We hypothesized that early antibiotic use could have decreased the sensitivity of diagnostic tests or that bioterrorism-related inhalational anthrax may include mild disease.
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